Biomechanical insights to prevent and treat kneecap instability

Patellar instability, a condition associated with partial or full dislocation of the patella (kneecap), is common among adolescent athletes and can significantly impact mobility and long-term joint health. This project aims to identify the anatomical and biomechanical factors that contribute to patellar instability, with the goal of guiding personalized treatment and improving outcomes. Through this work, we aim to influence clinical decision-making and enhance injury prevention and treatment.

What you’ll do: You will work with real patient data, including medical images, clinical exam records, and survey responses. You’ll gain experience in biomechanical simulation, machine learning, and statistical modeling to analyze knee structures and relate them to injury severity and treatment efficacy. No prior experience in these areas is required--Prof. Sinopoli will provide mentorship and training.

Beyond this project, you’ll have the chance to help build the Harvey Mudd Biomechanics Lab’s capabilities by setting up and testing experimental biomechanics equipment, such as force plates, cameras, and wearable sensors. You may also engage with potential clinical and athletic collaborators to extend the lab’s impact in healthcare and sports performance.

Want to learn more? Email Prof. Sinopoli at msinopoli@hmc.edu or stop by her office, Parsons 2363, Fridays before 11:30am.

Essay prompt: Please introduce yourself and be sure to include: why you are interested in this project and what you hope to learn or achieve through this experience; how this opportunity aligns with your academic and career goals; and the amount of time you would be able to commit to the project in the spring semester and summer (as applicable). (Please keep your response to ~300-400 words.)

Name of research group, project, or lab
Harvey Mudd Biomechanics Lab
Why join this research group or lab?

The Harvey Mudd Biomechanics Lab aims to improve health, mobility, and quality of life across the lifespan by studying human movement and performance. Our research uses a variety of techniques from biomechanical data science, musculoskeletal simulation, wearable sensing, medical imaging, statistical modeling, and machine learning to maintain and restore movement, reduce injury, improve treatment, and enhance performance.

Representative publication
Logistics Information:
Project categories
Engineering
Biomechanics
Biomedical Engineering
Machine Learning
Student ranks applicable
First-year
Sophomore
Junior
Senior
Student qualifications
  • Comfort with Python
  • Curiosity about research at the intersection of orthopaedics and engineering
  • Eagerness to learn skills in musculoskeletal simulation and data analysis
  • Ability to conduct research full-time and on campus from May 26-July 31
Time commitment
Summer - Full Time
Compensation
Paid Research
Number of openings
2
Techniques learned

Students will learn and improve skills among:

  • Research fundamentals (e.g., reviewing the literature, asking questions, designing experiments, scientific communication)
  • Python & code collaboration (e.g., GitHub)
  • Biomechanical modeling and simulation
  • Machine learning & statistical modeling
Project start
Summer 2025 or earlier
Contact Information:
Mentor
msinopoli@hmc.edu
Principal Investigator
Name of project director or principal investigator
Marissa Sinopoli
Email address of project director or principal investigator
msinopoli@hmc.edu
2 sp. | 2 appl.
Hours per week
Summer - Full Time
Project categories
Machine Learning (+3)
EngineeringBiomechanicsBiomedical EngineeringMachine Learning